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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Bull Math Biol. 2015 Mar 21;77(6):1013–1045. doi: 10.1007/s11538-015-0075-7

Fig. 6.

Fig. 6

Schematic drawing of the exocytosis cascade in β-cells. On the left, the insulin granules produced in Golgi network are transported in membrane-bound vesicles into extracellular space. On the right, the particular steps involved in the exocytosis of the insulin granules. The numbers stand for: 1) Re-supply 2) Priming 3) Domain Binding 4) Ca Triggering 5) Fusion 6) Pore Expansion 7) Insulin Release