Table 1. Characteristics of included studies for meta-analysis.
| Author (year) | Location | Study design | Sample size | Mean age, y | Main etiology | Male, % | Cut-off score | Endpoints | SAP, % | Definition of SAP | Study period |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Wu (2008) | USA | Retrospective | 17922 | Median: 53 | Biliary | 51 | 3 | Mortality | NA | NA | 2000–2001 |
| USA | Retrospective | 18256 | Median: 53 | Biliary | 49 | 3 | Mortality | NA | NA | 2004–2005 | |
| Singh (2008) | USA | Prospective | 397 | 52 | Biliary | 49 | 3 | Mortality, OF, persistent OF, PNes | 5 | 2012 criteria | 2005–2007 |
| Papachristou (2010) | USA | Prospective | 185 | 52 | Biliary | 51 | 3 | Mortality, SAP, PNes | 22 | 2012 criteria | 2003–2007 |
| Mounzer (2012) | USA | Prospective | 256 | Median: 51 | Biliary | 52 | 2 | Persistent OF | 24 | 2012 criteria | 2003–2010 |
| USA | Prospective | 397 | Median: 52 | Biliary | 49 | 2 | Persistent OF | 9 | 2012 criteria | 2005–2007 | |
| Chen (2013) | China | Retrospective | 497 | 54 | Biliary | 55 | 2, 3 | Mortality, SAP, OF, PNec | 20 | 1992 criteria | 2005–2010 |
| Cho (2013) | Korea | Retrospective | 299 | 52 | Alcohol | 70 | 3 | SAP, mortality | 7 | 2012 criteria | 2008–2010 |
| Khanna (2013) | India | Prospective | 72 | 41 | Biliary | 51 | 2 | SAP, PNes, mortality | 43 | 1992 criteria | 2010–2012 |
| Park (2013) | Korea | Retrospective | 303 | 52 | Alcohol | 71 | 2 | Mortality, SAP, PNes, OF | 10 | 1992 criteria | 2007–2010 |
| Senapati (2014) | India | Prospective | 246 | 42 | Alcohol | 62 | 3 | Mortality, OF, persistent OF, PNes, | 7 | 2012 criteria | 2011–2013 |
| Zhang (2014) | China | Retrospective | 155 | 52 | Alcohol | 59 | 3 | Mortality, SAP, PNes | 17 | 2012 criteria | 2010–2013 |
OF, organ failure; PNes, pancreatic necrosis; SAP, severe acute pancreatitis.