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. 2015 Jun 19;10(6):e0130412. doi: 10.1371/journal.pone.0130412

Table 3. Subgroup analyses for cohorts assessing the predictive value of BISAP ≥3 for mortality.

Subgroups Cohort, n DOR (95% CI) AUC Cochrane-Q P value I2
Study design
Prospective 3 16.79 (7.08–39.82) 0.90 1.23 0.54 0
Retrospective 6 13.59 (9.07–20.37) 0.83 11.75 0.04 57.4%
Sample size
≥ 300 5 12.49 (10.02–15.58) 0.87 4.89 0.30 18.1%
< 300 4 21.21 (5.36–84.00) 0.89 7.41 0.06 59.5%
Main etiology
Biliary 5 12.29 (10.41–14.51) 0.87 3.30 0.51 0
Alcohol 4 31.25 (8.29–117.81) 0.91 6.45 0.09 53.5
Location
USA 4 12.26 (10.16–14.79) 0.93 3.29 0.35 8.8%
Asia 5 24.68 (8.35–72.99) 0.89 7.72 0.10 48.2%
SAP%
≥ 10% 4 11.97 (5.32–26.94) 0.83 2.66 0.45 0
< 10% 3 37.85 (11.61–123.35) 0.92 3.16 0.21 36.8%