Table 4. Subgroup analyses for cohorts assessing the predictive value of BISAP ≥3 for severe acute pancreatitis defined by the latest 2012 Atlanta classification.
| Subgroups | Cohort, n | DOR (95% CI) | AUC | Cochrane-Q | P value | I2 |
|---|---|---|---|---|---|---|
| Study design | ||||||
| Prospective | 3 | 12.45 (5.08–30.53) | 0.90 | 3.51 | 0.17 | 43.1 |
| Retrospective | 3 | 25.09 (6.02–104.55) | 0.40 | 9.32 | 0.01 | 78.5 |
| Sample size | ||||||
| ≥ 300 | 2 | 20.61 (7.41–57.29) | - | 1.91 | 0.17 | 47.7 |
| < 300 | 4 | 17.84 (5.50–57.86) | 0.89 | 11.09 | 0.01 | 73 |
| Main etiology | ||||||
| Biliary | 2 | 9.36 (4.85–18.09) | - | 0.67 | 0.41 | 0 |
| Alcohol | 4 | 28.47 (8.70–93.10) | 0.91 | 9.92 | 0.02 | 69.8 |
| Location | ||||||
| USA | 2 | 9.36 (4.85–18.09) | - | 0.67 | 0.41 | 0 |
| Asia | 4 | 28.47 (8.70–93.10) | 0.91 | 9.92 | 0.02 | 69.8 |
| SAP% | ||||||
| ≥ 10% | 3 | 11.74 (4.38–31.46) | 0.31 | 6.09 | 0.05 | 67.1 |
| < 10% | 3 | 32.58 (9.12–116.38) | 0.91 | 4.80 | 0.09 | 58.3 |