Table 1. Values of bond formation kinetic parameters.
Symbol | Parameter | Value | Reference |
---|---|---|---|
l b | Equilibrium P-selectin/PSGL-1 bond length | 80 nm | [25] |
σ | Bond spring constant | 250,000 fN/ μm | [25] |
Unstressed rate of bond formation a | Varies; default is 10 s-1 | ||
γ | Reactive compliance | 3.9×10−5 μm | [28] |
The bond formation kinetic parameters used in the MAD model are given here.
aThe unstressed rate of bond formation is not experimentally determined, so it is explored as an additional variable.