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. 2015 Jun 19;10(6):e0128378. doi: 10.1371/journal.pone.0128378

Table 1. Values of bond formation kinetic parameters.

Symbol Parameter Value Reference
l b Equilibrium P-selectin/PSGL-1 bond length 80 nm [25]
σ Bond spring constant 250,000 fN/ μm [25]
kf,2D0 Unstressed rate of bond formation a Varies; default is 10 s-1
γ Reactive compliance 3.9×10−5 μm [28]

The bond formation kinetic parameters used in the MAD model are given here.

aThe unstressed rate of bond formation is not experimentally determined, so it is explored as an additional variable.