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ATXN2 KO upregulates levels of PABPC1 protein and mRNA. a A significant upregulation of the PABPC1/beta-ACTIN protein ratio in KO liver at age 6 months (7 Atxn2 −/− versus 7 Atxn2 +/+ tissues) was detected, as shown in a bar graph above and in an immunoblot below. b qPCR showed a subtle, but significant upregulation for the ratio Pabpc1/Tbp in KO liver at 6 months
