Figure 7.
Four hours after LPS administration brain protein levels of IL-6 were increased compared to saline and this response was higher in the control diet mice (A). LPS increased splenic IL-6 levels four hours after treatment in the control diet mice, but not in the DIO mice (B). LPS administration increased splenic levels of IL-1β four and twenty-four hours after administration in both the control and DIO mice, but IL-1β levels were at higher four hours (C). Bars represent means ±SEMs. Means marked with different letters (a, b or c) are significantly different from each other.