II.

Multivariate Cox Proportional Hazard Model for Recurrence-Free Survival (RFS)

Factor	Comparison	Hazard ratio	95% hazard ratio confidence limits		Pairwise P-value	Overall P-value
Pre-op PSA	1 unit increase	1.04	1.02	1.05	<0.0001
PTEN	Homo vs. no deletion	1.64	1.13	2.37	0.009	0.02
	Hemi vs. no deletion	1.28	0.84	1.95	0.25
Seminal vesicle invasion	Yes. vs. No	2.31	1.53	3.48	<0.0001
Gleason score	3 + 4 vs. ≤6	1.54	1.12	2.11	0.008	<0.0001
	4 + 3 vs. ≤6	2.34	1.59	3.45	<0.0001
	≥8 vs. ≤6	2.31	1.52	3.53	<0.0001