Table 2.
Amino acid residues at the binding sites of SPR-SSZ, SPR-NADP+, and SPR-SPR complexes
| SSZ | NADP+ | SPR Dimer |
| Interface | ||
| Gly11 | Gly11 | - |
| Ser13 | Ser13 | - |
| Arg14 | Arg14 | - |
| Gly15 | - | |
| Phe16 | Phe16 | - |
| Ala38 | - | - |
| Arg39 | Arg39 | - |
| - | Asn40 | - |
| - | Ala65 | - |
| - | Asp66 | - |
| - | Leu67 | - |
| - | - | Glu70 |
| Asn97 | Asn97 | - |
| Ala98 | - | - |
| Gly99 | - | - |
| Ser100 | - | - |
| - | - | Gly107 |
| - | - | Phe108 |
| - | - | Val109 |
| - | - | Asp110 |
| - | - | Leu111 |
| - | - | Ser114 |
| - | - | Val117 |
| - | - | Asn118 |
| - | - | Trp121 |
| - | - | Ala122 |
| - | Leu123 | - |
| - | - | Thr126 |
| - | - | Leu129 |
| - | - | Ser133 |
| - | - | Lys137 |
| - | Ile152 | - |
| - | Ser153 | - |
| - | - | Pro160 |
| - | - | Phe161 |
| - | - | Lys162 |
| - | - | Gly163 |
| - | - | Ala165 |
| Tyr167 | Tyr167 | - |
| - | - | Cys168 |
| - | - | Ala169 |
| - | Lys171 | - |
| - | - | Ala173 |
| - | - | Met176 |
| - | - | Leu177 |
| - | - | Val180 |
| - | - | Leu181 |
| - | - | Leu183 |
| - | - | Glu184 |
| - | Pro195 | - |
| - | Gly196 | - |
| - | Pro197 | - |
| Leu198 | Leu198 | - |
| Thr200 | Thr200 | - |
| Met202 | Met202 | - |
| - | Gln203 | - |
Cutoff distance: 3.6 Angstrom