Table 4.
Top ten of the significant GO processes, KEGG pathways and Panther pathways enriched with miRNA targets involved in endometriosis
| GO processes | Process | FDR | Target number |
|---|---|---|---|
| GO:0006355 | Regulation of transcription, DNA-dependent | 5.55032e-182 | 963 |
| GO:0007165 | signal transduction | 2.72922e-125 | 694 |
| GO:0007275 | Multicellular organismal development | 7.66 e -100 | 557 |
| GO:0045944 | Positive regulation transcription of from RNA polymerase II promoter | 4.43532e-86 | 378 |
| GO:0007399 | Nervous system development | 3.20348e-70 | 280 |
| GO:0007155 | Cell adhesion | 8. 37777e-68 | 342 |
| GO:0045893 | Positive regulation of transcription, DNA dependent | 3.78756e -66 | 301 |
| GO:0007268 | Transmission synaptic | 6.22556e-57 | 250 |
| GO:0055085 | Transmembrane transport | 9. 4472e-56 | 353 |
| GO:0000122 | Negative regulation transcription of from RNA polymerase II promoter | 1. 0109e-55 | 263 |
| KEGG pathways | Pathway | FDR | Target number |
|---|---|---|---|
| KEGG:5200 | Pathways in cancer | 3.54381e-53 | 218 |
| KEGG:4144 | Endocytosis | 5.04266e-44 | 144 |
| KEGG:4360 | Axon guidance | 5.91358e-35 | 101 |
| KEGG:4810 | Regulation of actin cytoskeleton | 2.65172e-34 | 140 |
| KEGG:4010 | MAPK signaling pathway | 4.03001e-33 | 162 |
| KEGG:4080 | Neuroactive ligand receptor | 5.56784e-29 | 158 |
| KEGG:4310 | Wnt signaling pathway | 5.87106e-29 | 105 |
| KEGG:4510 | Focal adhesion | 8.49293e-29 | 127 |
| KEGG:4060 | Cytokine signaling pathway | 4.84554 e-27 | 151 |
| KEGG:4062 | Chemokine signaling pathway | 1.23502e-26 | 119 |
| Panther pathways | Pathway | FDR | Target number |
|---|---|---|---|
| P00057 | Wnt signalling pathway | 3.24683e-35 | 173 |
| P00005 | Angiogenesis | 3.83276e-34 | 113 |
| P00034 | Integrin signalling pathway | 4.17619e-29 | 109 |
| P00047 | PDGF signalling pathway | 6.46839e-25 | 90 |
| P00031 | Inflammation mediated by chemokine cytokine signaling pathway | 3.43609e-23 | 119 |
| P00026 | Heterotrimeric G-protein signaling pathway---Gi alpha and Gs, and alpha mediated pathway | 3.32868e-23 | 98 |
| P00012 | Cadherin signalling pathway | 2. 44252e-19 | 88 |
| P00018 | EGF receptor signaling pathway | 2.29847e-18 | 75 |
| P00021 | FGF signaling Pathway | 7.78382e-18 | 72 |
| P00004 | Alzheimer disease --presenilin pathway | 4.27409e-17 | 75 |