Table 2.
Validation of bioinformatics software applications that were used in the present study
Antigen | Predicted epitopes | Experimental epitopes | Reference |
---|---|---|---|
GroEL1 of Yarsinia | 28-42,78-92,178-185,275-290,315-336,430-440,526-545 | 316-326 | 17 |
Dnak2 of Brucella | 40-67,78-92,210-227,357-370, 523-537, 609-640 | 617-637 | 9 |
Omp313 of Brucella | 25-28,46-73,122-127,175-182 | 48-74 | 18, 19 |
SOD 4 of Brucella | 44-50,70-86,134-153,147-165 | 75-86,136-150,149-162 | 20 |
Heat Shock Protein 60,
Heat Shock Protein 70,
Outer Membrane 31,
Sodium Oxide Dismutase
Similar epitopes between predicted epitopes using bioinformatics tools and experimental studies were emboldened and underlined