Table 1.

Effect of Adrb2 Deletion on RIS-Induced Trabecular Bone Loss

	Adrb2+/+		Adrb2−/−
	Vehicle (n = 10)	Risperidone (n = 10)	Vehicle (n = 11)	Risperidone (n = 11)
BV/TV, %	6.7 ± 0.5	5.6 ± 0.5	6.3 ± 0.4	5.7 ± 0.5
Tb.N, 1/mm	3.46 ± 0.08	3.06 ± 0.06a	3.37 ± 0.06	3.21 ± 0.10
Tb.Th, mm	0.045 ± 0.001	0.046 ± 0.002	0.043 ± 0.001	0.045 ± 0.002
Tb.Sp, mm	0.288 ± 0.008	0.328 ± 0.007a	0.295 ± 0.006	0.313 ± 0.010
Conn.D, 1/mm3	59 ± 8	35 ± 4b	63 ± 5	43 ± 5b

^aP < .01, comparing vehicle vs risperidone within each genotype.

^bP < .05, comparing vehicle vs risperidone within each genotype.