Figure 4.
Effects of blank-SAP (control) or NK3-SAP injections on TSKIN (A), HLI (B), and TCORE (C) in rats exposed to various TAMBIENT. A, At TAMBIENT of 11°C and 26°C, TSKIN was lower in NK3-SAP than in control rats. E2 reduced TSKIN in control rats at the TAMBIENT of 11°C and in NK3-SAP rats at the TAMBIENT of 26°C. B, At all 3 TAMBIENT, the lower levels of HLI in NK3-SAP rats indicates decreased skin vasodilation. C, At the high TAMBIENT of 33°C, the TCORE was reduced by E2 in both control and NK3-SAP rats. No differences were detected in TCORE between control and NK3-SAP rats. Values represent means ± SEM; n = 6 to 8 rats/group. *, Significantly different, blank-SAP vs NK3-SAP; +, significantly different after E2 treatment (within blank-SAP or NK3-SAP).