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. 2015 Jun 8;2015:148651. doi: 10.1155/2015/148651

Figure 2.

Figure 2

Conditional inactivation of Furin in the livers of ASV-B mice resulted in an increased tumor mass. (a) Conditional inactivation of Furin in the livers of ASV-B mice had a significant impact on the tumorigenic process. Already after 5 weeks the ratio of the tumor weight and the total body weight was significantly increased (27%) in the Furin KO mice. Student's t-test was used to determine statistical significance (n = 3–14). (b) A representative photograph of 19-week-old ASVB+/− Alb-Cre−/−  Furfl/fl mice. (c) A representative photograph of 19-week-old ASVB+/− Alb-Cre+/−  Furfl/fl mice.