Fig. 6.

Mitochondrial membrane dysfunction upon co-addition of laurate and oleate. Cells were stimulated by fatty acids for 6 h and then treated with TMRM. The histograms show the mean fluorescence intensities of untreated cells (shaded boxes) and co-stimulated cells (white boxes). Each data point is the population (%) of cells with the decreased mean fluorescence intensity (MFI) characteristic of mitochondria that have lost their membrane potential (Mit). The data are representative of at least three separate experiments.