Table 2.

Markers and Genomic Regions with LOD Scores >1.5 in Multipoint Linkage Analyses for Obesity Phenotype Variation and the Identified Candidate Genes inside the Genomic Regions

Phenotype and Chromosome Location	LODScore	QTLs in Animal Models
BMI:a
1p36 (0 cM from pter)	2.09	See table 1
2q14 (128 cM from pter)	4.44	See table 1
4q12 (68 cM from pter)	2.09	See table 1
6q27 (188 cM from pter)	1.61	See table 1
PFM:
2q14 (128 cM from pter)	2.10	1.9% Late weight gain (Cheverud et al. 1996; Vaughn et al. 1999)
8q24 (149 cM from pter)	1.54	14.4% 14-wk % Fat (Horvat et al. 2000); 24% body weight (Gauguier et al. 1996)
Fat mass:b
2q14 (128 cM from pter)	2.21	1.9% Late weight gain (Cheverud et al. 1996); Vaughn et al. 1999)
6q27 (188 cM from pter)	1.59	See table 1
20q13 (69 cM from pter)	1.64
Lean mass:
12q14 (82 cM from pter)	1.64
17p12 (33 cM from pter)	1.64
7p22 (5 cM from pter)	1.52	4.9% 14-wk % Fat (Horvat et al. 2000); 5.4% weight (Chung et al. 1997)

^aPGD, TNFR2, and NR0B2 are candidate genes for BMI. See table 1, footnote a.

^bSee “Discussion” section.