Table 6.

Association of Bcl-2 STR Alleles with Lymphocyte Count and CD4 T Cell Levels in UGRP/CEPH Families^[Note]

Bcl-2 STR Alleles	SampleSize	Pa	Corrected Pb
Lymphocyte count:
Allele 1	9	NS	NS
Allele 2	15	NS	NS
Allele 3	37	NS	NS
Allele 4	0	…	…
Allele 5	17	.03490	NS
Allele 6	7	<.000001	<.000006
CD4 T cell count:
Allele 1	9	NS	NS
Allele 2	15	NS	NS
Allele 3	37	NS	NS
Allele 4	0	…	…
Allele 5	17	NS	NS
Allele 6	7	.00128	.00768

Note.— QTDT was assessed for Bcl-2 alleles against lymphocyte count and CD4 T cell levels, using the method of George et al. (1999). Significant transmission distortion was seen for allele 6, for lymphocyte count and CD4 T cell level, indicating association in the presence of linkage. P values are only calculated for transmitted alleles. NS = not significant.

^aUncorrected significance level.

^bSignificance level with Bonferroni correction.