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. 2015 May 15;5(5):e312. doi: 10.1038/bcj.2015.38

Figure 5.

Figure 5

Len in combination with ACY1215 abrogates BMSC-induced c-Myc expression. (a) MM.1S and H929 cells were cultured for 48 h in the presence of BMSC-CS from five MM patients. (b) MM.1S cells were cultured for 48 h with BMSC-CS in the presence of Len. (c) MM.1S cells were cultured for 24 h with BMSC-CS in the presence of ACY1215 (2 μM), Len (1 μM) or both. Whole-cell lysates were subjected to immunoblotting with indicated Abs. (d) MM.1S cells were cultured for 48 h with BMSC-CS in the presence of ACY1215 and/or Len. Cell growth was assessed by MTT assay.