Table 3.

Polymorphisms Detected in FOXP2

		Frequency inIndividuals withc
Intron/Exonaand Positionb	Change	Autism(n=48)	SLI(n=43)
Intron 3:
−102 bp from exon 3a	T/A	9	11
Intron 3a:
−32 bp from exon 3b	A/G	0	1
−48 bp exon3bd	T/C	15	19
−68 bp from exon3b	G/A	1	0
Intron 5:
+17 bp from exon5	T/G	8	10
Intron 5/Exon 6:
…	Ins CAGCAG	0	1
Intron 11:
+9 bp from exon11	T/C	1	1
−80 bp from exon12	A/G	0	1
Intron 13:
+30 bp from exon13	C/G	1	2
Intron 14:
+24 bp from exon14	T/C	0	1
−44 bp from exon15	T/G	2	0
−58 bp from exon15	T/C	3	0

^aFor intron numbers, see figure 2.

^bPosition is given in relation to nearest exon; “−” denotes that the SNP is found 5′ to the exonic sequence, and “+” denotes that the SNP is found 3′ to the exonic sequence.

^cFrequency of heterozygotes within the sample tested.

^dPolymorphism used to type individuals for association analysis.