Figure 1. Comparison of aggregated amyloid formation by wild-type and A53E αS proteins following in vitro incubation.
K114 fluorometry (A) and sedimentation analysis (B) of wild-type (white) and A53E (black) αS following in vitro incubation at 1, 2.5 and 5 mg/ml for the number of days indicated. Error bars represent SEM. Significant differences were determined by t-tests. AFU; arbitrary fluorescence units, * p<0.05, ** p<0.005, *** p<0.001.