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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Shock. 2015 Mar;43(3):255–260. doi: 10.1097/SHK.0000000000000291

Figure 4. The severity of traumatic brain injury alters the maturation state of infiltrating monocyte-derived cells at 24 hours post injury.

Figure 4

Mild TBI did not produce a significant change in the proportion of monocytes within the injured brain. Mild TBI did result in a 1.4 fold increase in monocyte-derived (MD-Mϕ) macrophages (*=p<0.002). There was also a modest, albeit statistically significant, increase in inflammatory tissue macrophages and inflammatory (iDC) dendritic cells (#=p<0.04). Severe TBI resulted in a 2.2 fold increase in infiltrating monocytes, an 11.3 fold increase in MD-Mϕ, a 3.9 fold increase in iMϕ, and a 4.5 fold increase in iDC as compared to sham (◆=p<0.001).