TABLE 3.
Memory System | Major Anatomical Structures Involved | Length of Storage of Memory | Type of Awareness | Examples | Disorder that can Impair Memory |
---|---|---|---|---|---|
Semantic memory | Extrasylvian temporal lobes | Minutes to years | Explicit (associated with conscious awareness) or implicit | Knowing who was the first president of the United States, the color of a lion, and how a fork differs from a comb | Semantic dementia |
Episodic memory | Medial temporal lobes, hippocampus, anterior thalamic nucleus, mammillary body, fornix, prefrontal cortex | Minutes to years | Usually explicit | Remembering what you had for dinner last night and what you did for your last birthday | Alzheimer’s disease |
Procedural memory | Basal ganglia, cerebellum, parietal lobe, supplementary motor area, premotor cortex | Minutes to years | Usually implicit | Riding a bicycle, learning the sequence of numbers on a touchtone phone “by touch” | Ideational and ideomotor apraxia |
SECs |
Social: ventral prefrontal cortex Non-social: dorsal prefrontal cortex |
Minutes to years | Usually implicit |
Social: how to go on a date Non-social: how to set the clock on your VCR |
Behavioral-variant frontotemporal dementia |
Adapted with permission from Budson AE, Price BH: Memory dysfunction. N Engl J Med 2005; 352:692–699
SEC = structured event complex.