TABLE 5.
Predictions of the SEC/OCD Model for Idiopathic OCD and Symptoms of OCD Acquired from Brain Lesions
| Idiopathic OCD | OCD Symptoms Secondary to PFC Damage | OCD Symptoms Secondary to Basal Ganglia Damage | |
|---|---|---|---|
| Type of repetitive behavior | Complex | Simple and complex | Simple and complex |
| Executive dysfunction | Less | Yes | Less |
| Performance of SECs | Intact | Impaired | Intact |
| Anxiety | Yes | No | Less |
| Obsessions | Yes | No | Less |
| Associated with motor tics | Yes | No | Yes |
| Functional imaging | ↑ tracer uptake in OFC, caudate, ACC | ↓ tracer uptake in OFC, caudate, ACC | ↓ tracer uptake in basal ganglia (esp. caudate), ↑ in OFC |
SEC = structured event complexes; OCD = obsessive-compulsive disorder; OFC = orbitofrontal cortex; ACC = anterior cingulate cortex; PFC = prefrontal cortex