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. Author manuscript; available in PMC: 2015 Jun 22.
Published in final edited form as: J Neuropsychiatry Clin Neurosci. 2008 Fall;20(4):390–408. doi: 10.1176/appi.neuropsych.20.4.390

TABLE 5.

Predictions of the SEC/OCD Model for Idiopathic OCD and Symptoms of OCD Acquired from Brain Lesions

Idiopathic OCD OCD Symptoms Secondary to PFC Damage OCD Symptoms Secondary to Basal Ganglia Damage
Type of repetitive behavior Complex Simple and complex Simple and complex
Executive dysfunction Less Yes Less
Performance of SECs Intact Impaired Intact
Anxiety Yes No Less
Obsessions Yes No Less
Associated with motor tics Yes No Yes
Functional imaging ↑ tracer uptake in OFC, caudate, ACC ↓ tracer uptake in OFC, caudate, ACC ↓ tracer uptake in basal ganglia (esp. caudate), ↑ in OFC

SEC = structured event complexes; OCD = obsessive-compulsive disorder; OFC = orbitofrontal cortex; ACC = anterior cingulate cortex; PFC = prefrontal cortex