Fig. 2.

Innate immune pathways incorporating multiple positively selected genes. The positively selected genes in (a) the complement system and (b) the TLR signaling pathway are illustrated as darkened rectangles. Signaling cascades are depicted as arrows and inhibitors are depicted as blunt-ended lines. Defined pathways and complexes are highlighted in gray boxes with the given name. (c) Positively selected sites of the complement system alongside information on domain structure. Information on the function of these domains is also given.