Table 7.
Genes with decreased methylation that mapped to the Wnt/β-catenin pathway by IPA
| Symbol | Gene name | log2 Fold Change | Location | Type(s) |
|---|---|---|---|---|
| ACVR1C | activin A receptor, type IC | −3.029 | Plasma Membrane | kinase |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | −2.877 | Plasma Membrane | enzyme |
| SOX13 | SRY (sex determining region Y)-box 13 | −2.877 | Nucleus | transcription regulator |
| WIF1 | WNT inhibitory factor 1 | −2.877 | Extracellular Space | other |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | −2.708 | Plasma Membrane | other |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | −2.708 | Cytoplasm | phosphatase |
| TGFB3 | transforming growth factor, beta 3 | −2.708 | Extracellular Space | growth factor |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | −2.614 | Plasma Membrane | phosphatase |
| CSNK1G3 | casein kinase 1, gamma 3 | −2.515 | Cytoplasm | kinase |
| WNT11 | wingless-type MMTV integration site family, member 11 | −2.515 | Extracellular Space | other |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | −2.292 | Cytoplasm | kinase |
| WNT7A | wingless-type MMTV integration site family, member 7A | −2.292 | Extracellular Space | cytokine |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | −2.167 | Nucleus | transcription regulator |
| GJA1 | gap junction protein, alpha 1, 43 kDa | −2.029 | Plasma Membrane | transporter |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | −2.029 | Cytoplasm | phosphatase |
| PPP2R5A | protein phosphatase 2, regulatory subunit B’, alpha | −2.029 | Cytoplasm | phosphatase |
| SFRP2 | secreted frizzled-related protein 2 | −2.029 | Plasma Membrane | transmembrane receptor |
| SOX7 | SRY (sex determining region Y)-box 7 | −2.029 | Nucleus | transcription regulator |
| SOX14 | SRY (sex determining region Y)-box 14 | −2.029 | Nucleus | transcription regulator |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | −2.029 | Nucleus | transcription regulator |
| TLE3 | transducin-like enhancer of split 3 | −2.029 | Nucleus | other |
| WNT7B | wingless-type MMTV integration site family, member 7B | −2.029 | Extracellular Space | other |
| WNT8B | wingless-type MMTV integration site family, member 8B | −2.029 | Extracellular Space | other |