Table 5 . Intention-to-treat and per-protocol eradication rates in three treatment regimens .
Total enrolled patients(n=372) |
Group A(OABF) (n=124) | Group B(OABM-F) (n=124) |
Group C(OAF) (n=124) |
p |
Number of patients who have consumed >80% of drugs | 120 | 120 | 116 | |
ITT* eradication rate with 95% CI (n=372) | 83.7% (104/124) (95%CI=77.3-90.4) | 79.8% (99/124) (95%CI=72.6-87.0) | 84.6%(105/124) (95%CI=78.2-91.1) | 0.557 |
PP* eradication rate with 95% CI(n=356) | 86.6% (104/120)- (95%CI=80.5-92.8) | 82.5% (99/120) (95%CI=75.6-89.4) | 90.5%(105/116)-(95%CI=85.1-95.5) | 0.197 |
The cure rates was higher in treatment regimen C(OAF), but in general, the differences were not statistically significant (p=0.197, p=0.557, respectively for PP and ITT) and therefore, as far as helicobacter pylori eradication level is considered, the treatment regimen C(OAF) is in Grade B (good), and treatment regimen B(OABM-F) is in Grade D (poor) and treatment regimen A(OABF) is in Grade C (moderate or acceptable).