Table 2.

Early visual deprivation has significant effects on choline, creatine, myo-Inositol and possibly GABA concentrations in occipital but not precentral cortex. Median absolute concentrations (in millimolar, mM) and 25–75% interquartile range are shown for occipital and the precentral gyrus voxels. P-values represent Students t-tests corrected for 6 multiple comparisons using the Bonferroni-Holm method.

		Choline		Creatine		myo-inositol		NAA		GABA		Glutamate
		median	range	median	range	median	range	median	range	median	range	median	range
Occipital	SC	1.137	0.987–1.229	6.113	5.994–6.551	4.080	3.420–4.292	8.670	8.320–8.959	0.532	0.417–0.609	2.822	2.509–3.03
	EB	1.372	1.29–1.458	6.769	6.568–7.153	4.649	4.43–5.253	8.388	8.159–8.674	0.286	0.217–0.483	2.959	2.738–2.996
	% difference	18.7%		10.2%		13.0%		−3.3%		−60.2%		4.8%
	p	p>0.01		p<0.05		p<0.001				fails B-H correction
Precentral gyrus	SC	1.588	1.393–1.756	6.172	5.994–6.309	3.997	3.646–4.177	8.248	8.129–8.881	0.150	0.112–0.508	3.140	3.075–3.29
	EB	1.770	1.591-1.935	6.539	6.221–6.868	4.524	3.782–5.089	8.511	8.267–9.108	0.377	0.276–0.512	3.014	2.941–3.227
	% difference	10.8%		5.8%		12.4%		3.1%		86.2%		−4.1%
	p