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Oncogenic RAS genes protect against oxidative stress stimuli. RMS13 cells expressing EV, HRAS12V, KRAS12V, or NRAS12V were treated for 48 h with indicated concentrations of Auranofin (A), RSL3 (B), or Erastin (C). Cell viability was determined by MTT assay and cell density by crystal violet assay; results are expressed as percentage of untreated cells. Mean + SD of three independent experiments performed in triplicate are shown; *p < 0.05; **p < 0.01; ***p < 0.001.
