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. Author manuscript; available in PMC: 2016 Mar 17.
Published in final edited form as: Biochemistry. 2015 Mar 2;54(10):1976–1987. doi: 10.1021/bi501547k

Figure 2. Alignment of OXA-23, OXA-24/40 and two clinical variants containing a single P→S substitution.

Figure 2

The protein sequences for OXA-24/40, OXA-160, OXA-23 and OXA-225 were aligned using ClustalW. Identical residues between the two subfamilies are indicated by vertical hashes, and the site of the P→S substitution is highlighted in red (P227S in OXA-24/40; P225S in OXA-23). The site of proteolytic processing to generate the mature secreted protein is shown by a vertical green line.