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. Author manuscript; available in PMC: 2015 Jun 22.
Published in final edited form as: Leukemia. 2013 Mar 29;27(11):2177–2186. doi: 10.1038/leu.2013.91

Figure 1. H3K4me3 CHIP-Seq in primary MDS bone marrow CD34+ cells.

Figure 1

(a) Representative examples of H3K4me3 identified by CHIP-Seq in 11 genes in MDS (top) and control (bottom) BM CD34+ cells. Comparison between MDS and control samples indicate increased levels of H3K4me3 in the promoters of these genes in MDS CD34+ cells. (b) Logarithmic representation of Q-RTPCR results of 16 genes identified by CHIP-Seq in MDS and control CD34+ cells. These results confirm increased RNA expression in genes marked by higher levels of promoter H3K4me3 in MDS.