Table-II.
Gene | Genotype | Cases | % | Controls | % | OR(95%CI)1 | P value |
---|---|---|---|---|---|---|---|
ERCC1 rs11615 | TT | 63 | 42.57 | 135 | 45.3 | 1.0(Ref.) | - |
TC+CC | 85 | 57.43 | 163 | 54.7 | 1.12(0.74-1.70) | 0.58 | |
ERCC1 rs3212986 | GG | 79 | 53.38 | 169 | 56.71 | 1.0(Ref.) | - |
GA+AA | 69 | 46.62 | 129 | 43.29 | 1.14(0.75-1.73) | 0.5 | |
ERCC2 rs1799793 | GG | 84 | 56.76 | 201 | 67.45 | 1.0(Ref.) | - |
GA+AA | 64 | 43.24 | 97 | 32.55 | 1.58(1.03-2.41) | 0.03 | |
ERCC2 rs13181 | AA | 86 | 58.11 | 181 | 60.74 | 1.0(Ref.) | - |
AC+CC | 62 | 41.89 | 117 | 39.26 | 1.12(0.73-1.70) | 0.59 | |
NBN rs709816 | GG | 55 | 37.16 | 115 | 38.59 | 1.0(Ref.) | - |
GC+CC | 93 | 62.84 | 183 | 61.41 | 1.06(0.69-1.63) | 0.78 | |
NBN rs1805794 | GG | 52 | 35.14 | 127 | 42.62 | 1.0(Ref.) | - |
GC+CC | 96 | 64.86 | 171 | 57.38 | 2.66(1.73-4.08) | <0.001 | |
RAD51 rs1801320 | GG | 101 | 68.24 | 213 | 71.48 | 1.0(Ref.) | - |
GC+CC | 47 | 31.76 | 85 | 28.52 | 1.17(0.74-1.82) | 0.48 | |
RAD51 rs1801321 | GG | 88 | 59.46 | 187 | 62.75 | 1.0(Ref.) | - |
GT+TT | 60 | 40.54 | 111 | 37.25 | 1.15(0.75-1.75) | 0.5 | |
RAD51 rs12593359 | TT | 49 | 33.11 | 105 | 35.23 | 1.0(Ref.) | - |
TG+GG | 99 | 66.89 | 193 | 64.77 | 1.10(0.71-1.71) | 0.66 | |
XRCC3 rs861539 | CC | 77 | 52.03 | 173 | 58.05 | 1.0(Ref.) | - |
CT+TT | 71 | 47.97 | 125 | 41.95 | 1.28(0.84-1.93) | 0.23 |
Adjusted for sex, age and family history of cancer.