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. 2015 Mar-Apr;31(2):269–273. doi: 10.12669/pjms.312.6569

Table-II.

Genotype distribution of ten SNPs in NER and HRR pathways between cases and controls.

Gene Genotype Cases % Controls % OR(95%CI)1 P value
ERCC1 rs11615 TT 63 42.57 135 45.3 1.0(Ref.) -
TC+CC 85 57.43 163 54.7 1.12(0.74-1.70) 0.58
ERCC1 rs3212986 GG 79 53.38 169 56.71 1.0(Ref.) -
GA+AA 69 46.62 129 43.29 1.14(0.75-1.73) 0.5
ERCC2 rs1799793 GG 84 56.76 201 67.45 1.0(Ref.) -
GA+AA 64 43.24 97 32.55 1.58(1.03-2.41) 0.03
ERCC2 rs13181 AA 86 58.11 181 60.74 1.0(Ref.) -
AC+CC 62 41.89 117 39.26 1.12(0.73-1.70) 0.59
NBN rs709816 GG 55 37.16 115 38.59 1.0(Ref.) -
GC+CC 93 62.84 183 61.41 1.06(0.69-1.63) 0.78
NBN rs1805794 GG 52 35.14 127 42.62 1.0(Ref.) -
GC+CC 96 64.86 171 57.38 2.66(1.73-4.08) <0.001
RAD51 rs1801320 GG 101 68.24 213 71.48 1.0(Ref.) -
GC+CC 47 31.76 85 28.52 1.17(0.74-1.82) 0.48
RAD51 rs1801321 GG 88 59.46 187 62.75 1.0(Ref.) -
GT+TT 60 40.54 111 37.25 1.15(0.75-1.75) 0.5
RAD51 rs12593359 TT 49 33.11 105 35.23 1.0(Ref.) -
TG+GG 99 66.89 193 64.77 1.10(0.71-1.71) 0.66
XRCC3 rs861539 CC 77 52.03 173 58.05 1.0(Ref.) -
CT+TT 71 47.97 125 41.95 1.28(0.84-1.93) 0.23
1

Adjusted for sex, age and family history of cancer.