Table-III.
Stratification analysis on the association between rs699947 and rs2010963 and demographic characteristics in osteosarcoma risk.
| Variables | ERCC2 rs1799793 | OR(95%CI) | P | NBN rs1805794 | OR(95%CI) | P | ||
|---|---|---|---|---|---|---|---|---|
| Cases/Controls | Cases/Controls | |||||||
| GG | GA+AA | GA+AA vs GG | GG | GC+CC | GC+CC vs GG | |||
| Gender | ||||||||
| Male | 58/124 | 33/57 | 1.23(0.71-2.17) | 0.43 | 35/74 | 56/107 | 1.11(0.64-1.92) | 0.7 |
| Female | 26/77 | 31/38 | 2.42(1.20-4.87) | 0.007 | 17/53 | 40/62 | 2.01(1.07-4.23) | 0.04 |
| Age | ||||||||
| <20 | 53/34 | 119/45 | 1.70(0.94-3.05) | 0.06 | 31/69 | 56/95 | 1.31(0.74-2.34) | 0.32 |
| ≥20 | 31/82 | 30/50 | 1.59(0.82-3.06) | 0.14 | 21/58 | 40/74 | 1.49(0.76-2.97) | 0.21 |
| Family history of cancer | ||||||||
| Positive | 11/28 | 24/35 | 1.75(0.68-4.64) | 0.21 | 9/15 | 26/48 | 0.90(0.32-2.68) | 0.83 |
| Negative | 73/173 | 40/60 | 1.58(0.94-2.63) | 0.06 | 43/112 | 70/121 | 1.51(0.93-2.45) | 0.08 |