Table-III.
Stratification analysis on the association between VEGF -2578C/A and -460T/C and osteosarcoma risk by demographic characteristics
| Variables | VEGF -2578C/A | OR(95%CI)1 | P value | VEGF-460T/C | OR(95%CI)1 | P value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | |||||||||
| CC | CA+AA | CC | CA+AA | CA+AA vs CC | TT | TC+CC | TT | TC+CC | TC+CC vs TT | |||
| Age | ||||||||||||
| ≤20 | 27 | 54 | 39 | 47 | 1.66(0.85-3.27) | 0.11 | 23 | 58 | 32 | 54 | 1.49(0.74-3.03) | 0.23 |
| >20 | 35 | 60 | 45 | 45 | 1.71(0.91-3.22) | 0.07 | 25 | 70 | 34 | 56 | 1.7(0.87-3.34) | 0.09 |
| Gender | ||||||||||||
| Male | 38 | 71 | 50 | 59 | 1.58(0.89-2.83) | 0.1 | 30 | 79 | 41 | 68 | 1.59(0.86-2.93) | 0.11 |
| Female | 24 | 43 | 34 | 33 | 1.97(0.93-4.20) | 0.06 | 18 | 49 | 25 | 42 | 1.62(0.73-3.61) | 0.2 |
| Family history of cancer | ||||||||||||
| No | 59 | 101 | 77 | 86 | 1.53(0.95-2.45) | 0.06 | 44 | 116 | 61 | 102 | 1.58(0.96-2.60) | 0.06 |
| Yes | 3 | 13 | 7 | 6 | 5.06(0.75-39.15) | 0.05 | 4 | 12 | 5 | 8 | 1.87(0.29-12.49) | 0.44 |
1
Adjusted for sex, age and family history of cancer.