Table 2. Characteristics of Major Responders (CR/nPR).
Characteristic | CR + nPR (N=11) | NR (N=19) |
---|---|---|
Median age (range), y | 59 (47-78) | 59 (42-74) |
Male, no. (%) | 10 (91) | 15 (79) |
Median no. of prior regimens (range) | 1 (1-4) | 3 (1-8) |
Fludarabine-refractory disease, no. (%) | 3 (30) | 14 (78) |
Prior therapy with rituximab, no. (%) | 11 (100) | 19 (100) |
Prior therapy with alemtuzumab, no. (%) | 1 (9) | 3 (16) |
Rai stage III and IV, no. (%) | 3 (27) | 13 (68) |
Median β-2-microglobulin, mg/dL (range) | 2.5 (1.7-5.4) | 5.3 (2.4-9.5) |
CR indicates complete response; nPR, nodular partial response; NR, no response.