Table 7.

Corneal endothelial cell density in implanted eyes through month 60 in IMT-002-LTM

	Baseline	3 months	12 months	24 months	36 months	48 months	60 months
Age 65 to <75 years (group 1)
n	68	65	65	59	22	35	28
Mean ECD	2,444	1,984	1,866	1,775	1,569	1,618	1,552
95% CI	2,362, 2,525	1,849, 2,118	1,731, 2,002	1,637, 1,914	1,323, 1,815	1,429, 1,808	1,325, 1,779
Mean change in ECD		−18%	−23%	−27%	−33%	−32%	−35%
95% CI		−23, −13	−28, −18	−32, −21	−43, −24	−39, −25	−44, −27
Age ≥75 years (group 2)
n	119	111	102	94	39	42	29
Mean ECD	2,499	1,957	1,823	1,762	1,677	1,579	1,576
95% CI	2,433, 2,564	1,843, 2,072	1,703, 1,943	1,631, 1,893	1,475, 1,880	1,385, 1,772	1,333, 1,819
Mean change in ECD		−22%	−28%	−30%	−34%	−38%	−40%
95% CI		−26, −18	−32, −24	−35, −25	−41, −27	−45, −31	−48, −32

Note: Not all patients were available for all follow-up visits.

Abbreviations: CI, confidence interval; ECD, endothelial cell density.