Table 1.

Summary of Patients’ Clinical Courses

Patient	Age at Presentation	SFTPC Mutation	Family History	Age at MV Initiation	Maximum Respiratory Support	Age at Tracheostomy (mo)	LOS (mo)	Age at Decannulation (yr)	Respiratory Treatments	Support at Last Contact (Age)
1	7 d	c.545 G>C, .pGly182Arg	Positive	2 mo	CMV	3.5	19	6	Clearance, steroids, hydroxychloroquine	Room air (10 yr)
2	4 h	c.563 T>A, p. Leu188Gln	Negative	1 d	HFOV	3	10	5	Clearance, steroids, azathioprine	0.25 L NC (5 yr)
3	10 min	c.567 C>G, p.Cys189Trp	Negative	4 mo	HFOV	4.5	8	2	Steroids, azithromycin, hydroxychloroquine	Room air (3 yr)

Definition of abbreviations: CMV = conventional mechanical ventilation; HFOV = high-frequency oscillatory ventilation; LOS = hospital length of stay; MV = mechanical ventilation; NC = nasal cannula; SFTPC = surfactant protein C.