Table 1.
Clinical Baseline Characteristics of Study Population
| Control (n = 10) | Asthma (n = 10) | |
|---|---|---|
| Demographics | ||
| Age, yr | 38.8 (3.1) | 44.9 (3.1) |
| Sex, female/male | 5/5 | 5/5 |
| Race, black/white | 5/5 | 5/5 |
| Weight, kg | 78.9 (5.6) | 91.7 (4.7) |
| Height, cm | 169.9 (2.6) | 170.7 (3.2) |
| BMI | 27.04 (1.5) | 31.6 (1.7) |
| Severity, nonsevere/severe | N/A | 7/3 |
| Lung functions | ||
| FEV1% | 95.5 (5.9) | 77.0 (5.7)* |
| FVC% | 99.9 (6.5) | 87.2 (5.3) |
| FEV1/FVC | 0.80 (0.03) | 0.71 (0.02)* |
| PC20, mg/ml | >5.0 | 3.37 (1.61) |
| FeNO, ppb | 19.2 (3.4) | 21.6 (3.4) |
| Complete blood count | ||
| Neutrophils, % | 58.8 (2.5) | 61.2 (2.5) |
| Lymphocytes, % | 31.9 (2.1) | 27.3 (2.1) |
| Monocytes, % | 6.7 (0.4) | 8.0 (1.9) |
| Eosinophils, % | 2.1 (0.4) | 2.9 (0.6) |
| Basophils, % | 0.45 (0.01) | 0.60 (0.13) |
| Medication | ||
| Inhaled corticosteroids, n | 0 | 8 |
| Oral corticosteroids, n | 0 | 0 |
| Injectable corticosteroids, n | 0 | 0 |
Definition of abbreviations: BMI = body mass index; FeNO = fractional exhaled nitric oxide; N/A = not applicable; PC20 = provocative concentration of methacholine causing a 20% fall in FEV1.
All data are mean (SE).
*
P < 0.05 by t test.