Table 3.

Comparisons of Lymphoid Tissue Volumes between Participants with OSAS, Obese Control Subjects, and Lean Control Subjects

Population	Variable (mm3)	Adjusted Mean ± SE*			P Value†	Pairwise Comparisons‡
		OSAS	Obese Controls	Lean Controls		OSAS vs. Obese Controls	OSAS vs. Lean Controls	Obese vs. Lean Controls
All participants§	Adenoid	11,398 ± 514	8,429 ± 583	6,464 ± 518	3.1 × 10−9	0.0002	6.1 × 10−10	0.0153
	Tonsils	9,915 ± 528	7,205 ± 591	6,233 ± 521	6.4 × 10−6	0.0008	2.4 × 10−6	0.2325
Boys§	Adenoid	11,257 ± 635	9,643 ± 756	6,503 ± 637	5.2 × 10−6	0.1094	1.1 × 10−6	0.0025
	Tonsils	10,887 ± 661	7,899 ± 782	5,783 ± 651	2.5 × 10−6	0.0048	4.6 × 10−7	0.0465
Girls§	Adenoid	11,440 ± 878	6,563 ± 916	6,402 ± 875	0.0002	0.0005	0.0003	0.9040
	Tonsils	7,453 ± 704	6,120 ± 711	6,926 ± 678	0.4359	—	—	—

Definition of abbreviation: OSAS = obstructive sleep apnea syndrome.

^*Least squares mean and SE estimates from regression model adjusted for age at consent, race, Tanner stage, and sex (in all participants only).

^†Analysis of variance (P_ANOVA).

^‡P values for pairwise comparisons (P < 0.0167, indicating statistically significant after Bonferroni correction), applicable when P_ANOVA suggests significant differences between groups.

^§Bonferroni-corrected significance level of P_ANOVA < 0.025 (equals 0.05/2).