Fig 3. Impairments in novel object recognition at 3 and 6 months after PS1 knockdown in neural progenitor cells.

Percentage of time spent exploring the novel or familiar object by mice injected with either the control RL shRNA or PS1 shRNA at 3 (A) and 6 months (B). In contrast to RL-injected mice, PS1 shRNA-injected mice show no preference for the novel object at both time-points (unpaired t-test, *p<0.05). Error bars indicate ±SEM.