Table 3. Crude mortality incidence rate ratio among the vascular dementia and non-vascular dementia groups.
Variables | Vascular dementia (n = 2,142) | Degenerative dementia (n = 10,051) | ||||
---|---|---|---|---|---|---|
No medication | Nootropics | No medication | Nootropics | Anti-dementia medication | Both medications | |
(n = 750, 35.0%)) | (n = 1,392, 65.0%) | (n = 4,130, 41.1%) | (n = 4,850, 48.3%) | (n = 240, 2.4%) | (n = 831, 8.3%) | |
Age (mean ± SD) | 78.8 ± 6.8 | 77.9 ± 6.7 | 80.5 ± 7.4 | 78.8 ± 6.9 | 78.4 ± 6.3 | 76.7 ± 6.2 |
Charlson comorbidity index (CCI) | 2.29 ± 2.49 | 2.52 ± 2.58 | 1.77 .77.58 | 1.93 .93.58 | 1.38 ±.38 5 | 1.60 ±.60 5 |
CCI except dementia | 2.01 ± 2.34 | 2.20 ± 2.42 | 1.62 .62424 | 1.76 .76424 | 1.14 ±.1495 | 1.30 ±.30 5 |
Prescription cumulative days (IQR) | ||||||
Nootropics | 0 | 210 (63–577) | 0 | 140 (44–420) | 0.00 | 175 (58–511) |
Anti-dementia medication | 0 | 0 | 0 | 0 | 308 (90–739) | 336 (126–805) |
Median follow-up, years (IQR) | 2.04 (0.86–3.80) | 3.66 (1.91–6.03) | 1.79 (0.68–3.62) | 3.25 (1.57–5.41) | 3.04 (1.50–5.11) | 4.13 (2.35–6.37) |
Person-years at risk | 2,009 | 5,746 | 10,333 | 18,118 | 853 | 3729 |
Death | 415 | 593 | 2,321 | 2,077 | 64 | 218 |
Mortality incidence (/1000 py) | 207 | 103 | 225 | 115 | 75 | 58 |
Crude IRR (ref: non-dementia) (95% CI) | 2.82 (2.54–3.12) | 1.41 (1.29–1.54) | 3.07 (2.91–3.23) | 1.56 (1.48–1.65) | 1.02 (0.79–1.31) | 0.80 (0.69–0.91) |
SD: standard deviation; IQR: interquartile range; py: person-year; IRR: incidence rate ratio; CI: confidence interval