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. 2015 Jun 22;10(6):e0128142. doi: 10.1371/journal.pone.0128142

Table 2. Dropout rate and adverse effects of Rhodiola crenulata.

Groups Rhodiola (n = 38) Placebo (n = 19) p
Dropout, n (%) 5 (13.1) 1 (5.3) 0.65
Acute exacerbation, n 1 (2.6) 0 (0)
Poor appetite/upset, n 1 (2.6) 1 (5.3)
Loss to follow-up, n 2 (5.3) 0 (0)
No effect, n 1 (2.6) 0 (0)
Acute exacerbation 1 (2.6) 3 (15.8) 0.1
Common cold 13 (34.2) 4 (21) 0.3
Cough 7 (18.4) 2 (10.5) 0.7
Dyspnea 1 (2.6) 1 (5.3) 1
Upper airway dryness 1 (2.6) 0 (0) 1
Functional GI problems 5 (13.1) 1 (5.3) 0.65
Dizziness and giddiness 1 (2.6) 0 (0) 1
Gout 0 (0) 1 (5.3) 0.33
Severe adverse effect 0 (0) 0 (0) -
Any side effect 21 (55.3) 11 (57.9) 0.85

For definitions of acute exacerbation, please refer to text. GI: gastrointestinal. Chi square or Fisher’s exact test was used for comparisons.