Table 2. Dropout rate and adverse effects of Rhodiola crenulata.
Groups | Rhodiola (n = 38) | Placebo (n = 19) | p |
---|---|---|---|
Dropout, n (%) | 5 (13.1) | 1 (5.3) | 0.65 |
Acute exacerbation, n | 1 (2.6) | 0 (0) | |
Poor appetite/upset, n | 1 (2.6) | 1 (5.3) | |
Loss to follow-up, n | 2 (5.3) | 0 (0) | |
No effect, n | 1 (2.6) | 0 (0) | |
Acute exacerbation | 1 (2.6) | 3 (15.8) | 0.1 |
Common cold | 13 (34.2) | 4 (21) | 0.3 |
Cough | 7 (18.4) | 2 (10.5) | 0.7 |
Dyspnea | 1 (2.6) | 1 (5.3) | 1 |
Upper airway dryness | 1 (2.6) | 0 (0) | 1 |
Functional GI problems | 5 (13.1) | 1 (5.3) | 0.65 |
Dizziness and giddiness | 1 (2.6) | 0 (0) | 1 |
Gout | 0 (0) | 1 (5.3) | 0.33 |
Severe adverse effect | 0 (0) | 0 (0) | - |
Any side effect | 21 (55.3) | 11 (57.9) | 0.85 |
For definitions of acute exacerbation, please refer to text. GI: gastrointestinal. Chi square or Fisher’s exact test was used for comparisons.