Table 6. Portal bioavailability of XPP peptides—Effect of a meal matrix.
| Statistics | ||||||||
|---|---|---|---|---|---|---|---|---|
| Matrix | group | IPP (%) | LPP (%) | VPP (%) | Matrix/diet effect | XPP effect | Interaction | |
| protein | CasH2 | 54±12* | 55±13* | 59±15* | p1 | <0.0001 | 0.948 | 0.948 |
| meal | Basal | 100 | 100 | 100 | p2 | 0.859 | 0.872 | 0.999 |
| LQprot | 99±9 | 100±12 | 109±10 | |||||
| hCHO | 107±25 | 116±31 | 113±28 | |||||
| hFat | 95±15 | 79±15 | 106±23 | |||||
| Fiber | 99±29 | 113±54 | 106±32 | |||||
Portal bioavailability derived from the systemic response after an intra gastric bolus administrated of the tri-peptides isoleucine-proline-proline (IPP), leucine-proline-proline (LPP), valine-proline-proline (VPP) in a protein matrix (casein hydrolysate rich in XPP: CasH2) or in CasH containing meal matrix (Basal). Or in meals with different amount of macronutrients: low quality protein (LQprot), high amount of carbohydrates (hCHO + CasH), high amount of fat (hFat) or with fiber (Fiber). Portal bioavailability is expressed relative to Basal in %. Values are mean ± SEM. Basal: n = 10; hFat, LQprot, hCHO: n = 9; CasH2: n = 8. Significance: p<0.05.
p1: significance for comparison of protein matrix with meal matrix: Two-way ANOVA.
*): p<0.05 significance for comparison IPP, LPP or VPP portal availability of CasH2 relative to Basal with post-hoc Wilcoxon signed Rank test.
p2: significance for comparison meal matrixes: Two-way ANOVA.