Table 1. General characteristics of the study population (median with 25th/75th percentile).
| Subjects without increased IMT | Subjects with increased IMT | P | ||
|---|---|---|---|---|
| (n = 1489) | (n = 510) | |||
| Age (years) | 61 (54; 69) | 62 (54; 70) | 0.11 | |
| % male | 51.8 | 52.0 | 0.94 | |
| Smoking (%) | Ex-smoker | 40.5 | 39.8 | 0.21 |
| Smoker | 17.5 | 20.9 | ||
| Nonsmoker | 42.0 | 39.3 | ||
| % Physically active | 35.9 | 30.4 | 0.02 | |
| WHR | 0.89 (0.82; 0.95) | 0.90 (0.83; 0.95) | 0.15 | |
| eGFR (mL/min/1.73m2) | 74 (66; 83) | 74 (65; 82) | 0.30 | |
| Hypertensive (%) | 65.4 | 78.4 | < 0.001 | |
| Diabetes mellitus (%) | 15.1 | 24.2 | < 0.001 | |
| cIMT (mm) | 0.83 (0.76; 0.93) | 1.12 (0.99; 1.27) | < 0.001 | |
| ADMA (μmol/L) | 0.69 (0.61; 0.79) | 0.70 (0.62; 0.79) | 0.17 | |
| SDMA (μmol/L) | 0.47 (0.40; 0.55) | 0.48 (0.41; 0.58) | 0.05 | |
| ARG (μmol/L) | 150.1 (119.4; 184.6) | 152.2 (122.3; 188.4) | 0.34 | |
| DMA (μmol/L) | 1.18 (1.04; 1.31) | 1.19 (1.06; 1.36) | 0.07 | |
| ARG/ADMA | 218.5 (168.9; 266.5) | 211.9 (170.9; 270.3) | 0.81 | |
| Plaque (%) | 67.12 | 83.07 | < 0.001 |
Data are represented as median (interquartile range), or n (%). WHR indicates waist-to-hip ratio; eGFR, estimated-glomerular-filtration-rate; cIMT, carotid intima-media-thickness; ADMA, asymmetrical dimethylarginine; SDMA, symmetrical dimethylarginine; ARG, ˪-Arginine; DMA, dimethylarginine; ARG/ADMA, Arginine-asymmetrical dimethylarginine ratio.