Table 2. Phenotypical data of mice fed the HFpu or HFs diet for 27 weeks.
| HFpu | HFs | p-value | |
|---|---|---|---|
| Cumulative feed intake (kg) | 0.350 ± 0.007 | 0.339 ± 0.005 | n.s. |
| Serum insulin (nM) | 2.36 ± 0.17 | 1.92 ± 0.20 | n.s. |
| Serum glucose (mM) | 6.90 ± 0.19 | 7.16 ± 0.15 | n.s. |
| Serum leptin (nM) | 6.13 ± 0.71 | 5.67 ± 0.94 | n.s. |
| Serum adiponectin (mg L-1) | 15.5 ± 1.10 | 18.9 ± 1.35 | n.s. |
| Serum triacylglycerols (g L-1) | 6.02 ± 0.29 | 6.69 ± 0.57 | n.s. |
| WAT mitochondrial density (ratio to HFpu) | 1.00 ± 0.09 | 0.87 ± 0.07 | n.s. |
| eWAT weight (g) | 0.795 ± 0.067 | 0.866 ± 0.036 | n.s |
| Liver triacylglycerol (mg g-1 liver) | 52.7 ± 3.30 | 66.1 ± 3.02 | 0.007 |
| Muscle triacylglycerols (mg g-1 muscle) | 17.9 ± 1.61 | 22.9 ± 1.67 | 0.045 |
| Serum aspartate transaminase activity (μM s-1) | 0.69 ± 0.06 | 1.07 ± 0.12 | 0.009 |
| Serum alanine transaminase activity (μM s-1) | 0.83 ± 0.06 | 1.51 ± 0.16 | <0.001 |
Data are expressed as mean ± SEM (n = 11 for HFpu and n = 12 for HFs). All parameters were measured after 27 weeks of HFpu or HFs feeding and when mice were in a fasted state. The cumulative feed intake is calculated from the total feed intake between week 4 and week 27. eWAT weight represents the weight of the right epididymal WAT depot only. n.s. non-significant.