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. 2015 Jun 22;10(6):e0129536. doi: 10.1371/journal.pone.0129536

Table 2. Neonatal and childhood major outcomes at birth and 1–5 years old according to maternal pre-pregnancy body mass index and gestational weight gain categories.

Pre-pregnancy BMI (kg/m2) Poverall IOM categories Poverall
<24 (Group A) 24–27.9 (Group B) ≥28 (Group C) Inadequate (Group D) Adequate (Group E) Excessive (Group F)
No. of subjects 823 335 105 156 394 713
At birth e
Birth weight for length for gestational age Z score 0.09 (0.09) 0.38 (0.10) * 0.69 (0.14) # ^ <0.001 -0.32 (0.12) & 0.04 (0.10) 0.55 (0.09) <0.001
At 1–5 years old
Weight for length/height Z score
 Model 1 a 0.38 (0.08) 0.60 (0.09) * 0.84 (0.12) # ^ <0.001 0.33 (0.11) 0.35 (0.09) 0.65 (0.08) <0.001
 Model 2 b 0.43 (0.08) 0.60 (0.09) * 0.78 (0.12) # <0.001 0.45 (0.11) 0.41 (0.09) 0.61 (0.08) <0.001
Body mass index for age Z score
 Model 1 a 0.34 (0.08) 0.55 (0.09) * 0.78 (0.13) # ^ <0.001 0.30 (0.11) 0.30 (0.09) 0.59 (0.09) <0.001
 Model 2 b 0.38 (0.08) 0.54 (0.09) * 0.73 (0.12) # <0.001 0.40 (0.11) 0.35 (0.09) 0.56 (0.08) <0.001
Change in weight for height Z score from birth to 1–5 years old
 Model 1 a 0.29 (0.11) 0.22 (0.12) 0.15 (0.17) 0.53 0.65 (0.14) & 0.31 (0.12) 0.10 (0.11) <0.001
 Model 2 b 0.08 (0.08) 0.25 (0.09) * 0.42 (0.12) # <0.001 0.09 (0.11) 0.05 (0.09) 0.26 (0.08) <0.001

Data represent mean (SE), or percentage.

a, Adjusted for maternal age, family history of diabetes, education, family income, gestational diabetes treatment during pregnancy, gestational weeks of birth and infant feeding.

b, Adjusted for above variables and also birth weight for length for gestational age Z score.

* P <0.05 for Groups of A and B;

# P<0.05 for groups of A and C;

^ P<0.05 for groups of B and C;

& P for groups of D and E;

P <0.05 for Groups of E and F;

P<0.05 for groups of D and F.