Table 2. Neonatal and childhood major outcomes at birth and 1–5 years old according to maternal pre-pregnancy body mass index and gestational weight gain categories.
Pre-pregnancy BMI (kg/m2) | Poverall | IOM categories | Poverall | |||||
---|---|---|---|---|---|---|---|---|
<24 (Group A) | 24–27.9 (Group B) | ≥28 (Group C) | Inadequate (Group D) | Adequate (Group E) | Excessive (Group F) | |||
No. of subjects | 823 | 335 | 105 | 156 | 394 | 713 | ||
At birth e | ||||||||
Birth weight for length for gestational age Z score | 0.09 (0.09) | 0.38 (0.10) * | 0.69 (0.14) # ^ | <0.001 | -0.32 (0.12) & | 0.04 (0.10) | 0.55 (0.09) † ‡ | <0.001 |
At 1–5 years old | ||||||||
Weight for length/height Z score | ||||||||
Model 1 a | 0.38 (0.08) | 0.60 (0.09) * | 0.84 (0.12) # ^ | <0.001 | 0.33 (0.11) | 0.35 (0.09) | 0.65 (0.08) † ‡ | <0.001 |
Model 2 b | 0.43 (0.08) | 0.60 (0.09) * | 0.78 (0.12) # | <0.001 | 0.45 (0.11) | 0.41 (0.09) | 0.61 (0.08) † ‡ | <0.001 |
Body mass index for age Z score | ||||||||
Model 1 a | 0.34 (0.08) | 0.55 (0.09) * | 0.78 (0.13) # ^ | <0.001 | 0.30 (0.11) | 0.30 (0.09) | 0.59 (0.09) † ‡ | <0.001 |
Model 2 b | 0.38 (0.08) | 0.54 (0.09) * | 0.73 (0.12) # | <0.001 | 0.40 (0.11) | 0.35 (0.09) | 0.56 (0.08) † | <0.001 |
Change in weight for height Z score from birth to 1–5 years old | ||||||||
Model 1 a | 0.29 (0.11) | 0.22 (0.12) | 0.15 (0.17) | 0.53 | 0.65 (0.14) & | 0.31 (0.12) | 0.10 (0.11) † ‡ | <0.001 |
Model 2 b | 0.08 (0.08) | 0.25 (0.09) * | 0.42 (0.12) # | <0.001 | 0.09 (0.11) | 0.05 (0.09) | 0.26 (0.08) † | <0.001 |
Data represent mean (SE), or percentage.
a, Adjusted for maternal age, family history of diabetes, education, family income, gestational diabetes treatment during pregnancy, gestational weeks of birth and infant feeding.
b, Adjusted for above variables and also birth weight for length for gestational age Z score.
* P <0.05 for Groups of A and B;
# P<0.05 for groups of A and C;
^ P<0.05 for groups of B and C;
& P for groups of D and E;
† P <0.05 for Groups of E and F;
‡ P<0.05 for groups of D and F.