Table 4. Neonatal and childhood major outcomes at birth and 1–5 years old according to joint status of maternal pre-pregnancy body mass index and gestational weight gain.
Maternal pre-pregnancy BMI (kg/m2) and gestational weight gain | Poverall | ||||
---|---|---|---|---|---|
Pre-pregnancy BMI <24/non-excessive gestational weight gain (Group AA) | Pre-pregnancy BMI ≥24/non-excessive gestational weight gain (Group BA) | Pre-pregnancy BMI <24/excessive gestational weight gain (Group AB) | Pre-pregnancy BMI ≥24/excessive gestational weight gain (Group BB) | ||
No. of subjects | 469 | 81 | 354 | 359 | |
At birth a | |||||
Birth weight for length for gestational age Z score | -0.09 (0.10) | -0.06 (0.15) | 0.44 (0.11) # ^ | 0.62 (0.10) & † ‡ | <0.001 |
At 1–5 years old | |||||
Weight for length/height Z score | |||||
Model 1 a | 0.30 (0.09) | 0.48 (0.13) | 0.53 (0.09) # | 0.72 (0.09) & † ‡ | <0.001 |
Model 2 b | 0.38 (0.09) | 0.54 (0.13) | 0.52 (0.09) | 0.68 (0.09) & ‡ | <0.001 |
Body mass index for age Z score | |||||
Model 1 a | 0.26 (0.09) | 0.43 (0.14) | 0.49 (0.10) # | 0.66 (0.09) & ‡ | <0.001 |
Model 2 b | 0.33 (0.09) | 0.49 (0.14) | 0.48 (0.10) # | 0.62 (0.09) & | 0.001 |
Change in weight for height Z score from birth to 1–5 years old | |||||
Model 1 a | 0.39 (0.12) | 0.53 (0.18) | 0.10 (0.13) # ^ | 0.11 (0.12) & † | <0.001 |
Model 2 b | 0.03 (0.09) | 0.19 (0.13) | 0.17 (0.09) | 0.32 (0.09) & ‡ | <0.001 |
Data represent mean (SE), percentage or odd ratio (95% CI).
a, Adjusted for maternal age, family history of diabetes, education, family income, gestational diabetes treatment during pregnancy, gestational weeks of birth and infant feeding.
b, Adjusted for above variables and also birth weight for length for gestational age Z score.
* P <0.05 for Groups of AA and BA;
# <0.05 for groups of AA and AB;
& for groups of AA and BB;
^ P <0.05 for Groups of BA and AB;
† <0.05 for groups of BA and BB;
‡ for groups of AB and BB.