Table 4. Correlation coefficients between the follow-up mRS outcome and the three optional parameters (lesion volume, age, and admission NIHSS), the lesion-based t-score sum, as well as lesion overlap measures of the predefined MNI brain structures and automatically determined problem-specific VOIs.

Parameter or Brain Structure	Left	Right
Lesion Volume	0.589 (n = 37, p<0.001)	0.796 (n = 31, p<0.001)
Age	-0.074 (n = 37, p = 0.663)	-0.084 (n = 31, p = 0.654)
Admission NIHSS	0.651 (n = 37, p<0.001)	0.384 (n = 31, p = 0.033)
t-score Sum	0.783 (n = 37, p<0.001)	0.808 (n = 31, p<0.001)
Caudate	0.308 (n = 17, p = 0.230)	0.216 (n = 22, p = 0.334)
Insula	0.656 (n = 30, p<0.001)	0.620 (n = 25, p = 0.001)
Putamen	0.461 (n = 25, p = 0.020)	0.354 (n = 24, p = 0.089)
Thalamus	0.329 (n = 12, p = 0.296)	0.186 (n = 16, p = 0.489)
Cerebellum	- (n = 0)	- (n = 1)
Frontal Lobe	0.142 (n = 20, p = 0.549)	0.644 (n = 21, p = 0.002)
Occipital Lobe	0.044 (n = 10, p = 0.904)	0.512 (n = 7, p = 0.240)
Parietal Lobe	0.224 (n = 22, p = 0.316)	0.741 (n = 18, p<0.001)
Temporal Lobe	0.574 (n = 21, p = 0.007)	0.601 (n = 20, p = 0.005)
Problem-specific VOI 1	0.422 (n = 31, p = 0.018)	0.755 (n = 28, p<0.001)
Problem-specific VOI 2	0.601 (n = 30, p<0.001)	0.628 (n = 29, p<0.001)
Problem-specific VOI 3	0.567 (n = 31, p = 0.001)	0.819 (n = 29, p<0.001)
Problem-specific VOI 4	0.672 (n = 33, p<0.001)	0.642 (n = 27, p< 0.001)