Table 5. Englerin A and B plasma levels and effects on animal health in anesthetized rat experiments.

Compound	Dose	Experimental animal #	Compound concentration in blood	Outcome
Englerin A	0.03 mg/kg	15	30 nM	Increase MAP
	0.03 mg/kg	8	63 nM	Increase MAP
	0.03 mg/kg	7	132 nM	Animal died
	0.1 mg/kg	8	544 nM	Animal died
Englerin B	0.3 mg/kg	9	362 nM	No effect
	0.3 mg/kg	10	462 nM	No effect
	0.3 mg/kg	11	442 nM	No effect
	0.3 mg/kg	12	539 nM	No effect