Table 4.

Adverse events n (%)

	I: rSK schedule A	II: rSK schedule B	III: Hydrocortisone
n	170	170	170
Total subjects with adverse events	5 (2.9)	7 (4.1)	11 (6.5)
Events
Anal pruritus	2 (1.2)	4 (2.4)	2 (1.2)
Rectal bleeding	2 (1.2)	1 (0.6)	1 (0.6)
Anal fissure	1 (0.6)	0	3 (1.8)
Headache	1 (0.6)	2 (1.2)	0
Anal pain	0	0	2 (1.2)
Local burning sensation	1 (0.6)	0	1 (0.6)
Tenesmus	1 (0.6)	0	1 (0.6)
Constipation	0	0	1 (0.6)
Diarrhea	0	0	1 (0.6)
Discomfort due to mass sensation	1 (0.6)	0	0
Edema	0	0	1 (0.6)
Stroke	0	0	1 (0.6)

rSK: Recombinant streptokinase.