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. 2015 Jun 21;21(23):7335–7342. doi: 10.3748/wjg.v21.i23.7335

Table 1.

Summary of reported cases of liver carcinosarcoma with combined hepatocellular cholangiocarcinoma

Ref. Age (yr) Sex Positive tumor marker HBV HCV Cirrhosis Size (cm) Sarcoma element Treatment Metastasis Outcome
Nakajima et al[2] 74 M - - NA Precirrhotic fibrosis 15 × 13 Pleomorphic cells, spindle shaped cells, and osteoplastic cells Mitomycin C Liver, lung, lymph nodes, stomach, peritoneum Died within 5 mo
Papotti et al[3] 59 M - - - - 4.0 × 5.2 Spindle cells Right hepatectomy PVTT Died within 4 mo
Goto et al[1] 73 M AFP + NA + 3 × 2.5 × 2 Chondrosarcoma, osteosarcoma Segmentectomy - 19 mo, alive
CEA
CA19-9
DCP
Present case 45 M AFP + - + 7 × 5 Chondrosarcoma, osteosarcoma, spindle cells, and bizarre cells Segmentectomy Diaphragm 7 mo, alive
CA 12-5

AFP: Alfa-fetoprotein; CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; DCP: Des-γ-carboxy prothrombin; HBV: Hepatitis B virus; HCV: Hepatitis C virus; NA: Not available; PVTT: Portal vein tumor thrombus.